Butyric Acid: Discover The Incredible Health Benefits Of ...
Nov. 27, 2024
Butyric Acid: Discover The Incredible Health Benefits Of ...
Butyric acid is a vital fatty acid produced when the good bacteria in the gut break down dietary fibre. It is naturally found in animal fats and vegetable oils, however, the quantity of butyric acid found in food sources is less compared to the amount produced in the gut.
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What is Butyric Acid?
Butyric acid is known as a short-chain fatty acid (SCFA), which is one among the three most common SCFA&#;s in the gut, along with acetic acid and propionic acid. These saturated fatty acids comprise about 90-95 % of the SCFAs in the gut that is produced when gut-friendly bacteria break down dietary fibre. Butyric acid is well-known to support digestive health, reduce inflammation and lowers the risk of diseases and promote overall health. It holds a significant role in providing colon cells with the needed energy to carry out its normal functions and also regulates blood sugar and cholesterol levels. It goes by other names such as butyrate and butanoic acid.
Incredible Health Benefits Of Butyric Acids
Fuels Gut
Butyric acid serves as a chief source of energy for colon cells, which make up the lining of the intestine. While most of the body cells utilise glucose as the main source of energy, the colon cells lining gut chiefly use butyrate, without butyrate these cells are unable to perform normal functions. The short-chain fatty acids offer an oxygen-free environment that supports the growth of gut microbes that controls inflammation and maintain gut cells healthy.
Also Read: Prebiotics: 5 Awesome Foods That Uphold Gut Health-Infographic
Potent Antioxidant Effects
Butyrate guards the cells against detrimental substances to keep gut healthy and disease-free. A colon is a storage place of the waster products. Higher levels of butyrate have shown to increase levels of glutathione, an antioxidants made in the system which neutralises free radicals in the gut. This improves the barrier function of the colonocytes and lowers the risk of bowel cancer, inflammatory bowel disease (IBD), and irritable bowel syndrome (IBS).
Prevents Cancer
Regular intake of high fibre diet increases the amount of butyric acid produced in the gut which is well-known to reduce the risk of colon cancer. Studies have proven that butyric acid is a potential to prevent and treat colon cancer by blocking the growth of colorectal tumour cells. Moreover, it also leads to apoptosis that stops the growth of cancer cells completely.
Manages Diabetes
Studies show that butyrate stimulates the secretion of gut hormones such as glucagon &#;like-peptide -1(GLP-1) and peptide YY (PYY).GLP-1 hormones increase insulin secretion and lower the production of glucagon in the pancreas. While the PYY hormones promote the uptake of glucose in muscles and fatty tissue. Thus the presence of butyric acid increases the secretion of gut hormones that regulate type 2 diabetes and control weight
Boosts Brain Health
Butyric acid plays a key role in promoting neuroprotective effects that trigger brain and nervous system function. Butyrate targets several pathways linked with the progression of neurodegenerative diseases like Parkinson&#;s, Alzheimer&#;s stroke and autism. A diet abundant in butyric acid is an effective way to improve disease outcomes and uplift overall health.
Food Sources Rich In Butyric Acid
Generally, most of the butyric acid in the body is made from the gut bacteria. While some amount of butyric acid is also found naturally in food sources which include:
Ghee
Cow&#;s milk
Butter
Sheep&#;s milk
Breast milk
Parmesan cheese
Red meat
Vegetable oils
Sauerkraut
Butter is one of the richest sources of butyric acid. It is also available in the form of dietary supplement as sodium butyrate. However, increasing the intake of dietary fibre can also help to boost butyric acid level in the gut. The gut bacteria chiefly feed on resistant starches which the body can&#;t break down. Some of the good sources of resistant starches, pectin found in many fruits and inulin.
Also Read: Dietary Fibre And Its Role In Preventing Chronic Diseases
Garlic
Onions
Asparagus
Potatoes
Bananas
Apples
Apricots
Carrots
Oat bran
Conclusion:
Butyric acid is one of the most beneficial short-chain fatty acids that play a key role in uplifting digestive health, reduces inflammation, protects the brain, manages weight and prevent cancer. The gut bacteria in the body make butyrate from the foods you can&#;t digest, which renders the body with a host of health benefits. Enriching your diet with fibre will help to elevate the butyric acid production by the gut flora.Disclaimer:
Butyric acid is one of the most beneficial short-chain fatty acids that play a key role in uplifting digestive health, reduces inflammation, protects the brain, manages weight and prevent cancer. The gut bacteria in the body make butyrate from the foods you can&#;t digest, which renders the body with a host of health benefits. Enriching your diet with fibre will help to elevate the butyric acid production by the gut flora.
The content provided here is for informational purposes only. This blog is not intended to substitute for medical advice, diagnosis, or treatment. Always seek the advice of a qualified healthcare provider for any questions or concerns you may have regarding a medical condition. Reliance does not endorse or recommend any specific tests, physicians, procedures, opinions, or other information mentioned on the blog.
About Butyric Acid Supplements - Tesseract
Updated on September 16,
Are you considering including butyric acid supplements in your diet? Butyric acid has numerous health benefits, including promoting gastrointestinal and neurological health.* But when do you need a butyric acid supplement? What are the best butyric acid supplements? And are butyric acid supplements safe?
This article answers all these questions about this multi-functional molecule and why taking an advanced butyric acid supplement may be beneficial. Use the links below to jump to specific topics about butyric acid and butyric acid supplements.
The Basics of Butyric Acid: An Overview
Butyric acid, or butyrate, is a short-chain fatty acid (SCFA) produced in the large intestine when beneficial gut bacteria ferment dietary fiber. Butyric acid can also be consumed from plant oils, animal fats, and nutritional supplements. Butyric acid is a multi-functional molecule known for its distinctive strong odor and wide range of health benefits.
Butyric acid&#;s health benefits are attributed to the following:
- Epigenetic regulator: Epigenetic regulators are specific molecules that control the expression of certain genes. Butyric acid acts as an epigenetic regulator to inhibit DNA synthesis in cells exhibiting abnormal growth and regulates cell growth and division by inducing changes in gene expression1.*
- Energy substrate: Butyric acid is the primary energy source for colon cells (colonocytes), contributing to 60-70 percent of their energy requirement2.*
- Transmembrane protein activator: Butyric acid activates several transmembrane proteins involved in multiple cell signaling pathways3.*
Why Might You Need A Butyric Acid Supplement?
Butyric acid naturally occurs in milk, hard cheese (such as parmesan), butter, cream, yogurt, fermented soy, pickled cucumber, and other foods. Additionally, plant products containing dietary fibers are a particularly good source of endogenous production of butyric acid through bacterial fermentation. A diet rich in legumes, whole grains, fruits and vegetables, nuts and seeds, and dairy products helps your body maintain an optimal butyric acid level.
So, why do you need a butyric acid supplement? You should consider adding a butyric acid supplement to your diet when:
- A fiber-rich diet does not suit you. Certain gastrointestinal conditions make digesting a large amount of fiber uncomfortable or even painful. Other gastrointestinal conditions can make it challenging to increase butyrate levels through dietary fiber intake alone. In addition, many consuming a Western diet find it difficult, if not impossible, to eat an adequate amount of fiber on a daily basis.
- The gut microbiome fails to produce the necessary amount of butyrate. Individuals who have certain gastrointestinal disorders may have low butyric acid levels because the inflamed gastrointestinal mucosa cannot absorb any butyrate that is produced. Other conditions where dysbiosis (negative alterations in populations of gut microbes) is present, decrease the formation of butyric acid(4). Even with the recommended dietary fiber intake, your intestines might not produce the required amount of butyrate.
Under such conditions, a butyric acid supplement can be a suitable alternative (or addition) to a fiber-rich diet.
Raw Butyric Acid versus Butyric Acid Supplements
Conventional butyrate supplementation is achieved through oral ingestion of butyrate mineral salts or through the use of a sodium butyrate enema. However, when sodium butyrate salt comes in contact with moisture, it emits a strong, distinctive, and foul odor, making it difficult to ingest orally. On the other hand, a sodium butyrate enema is less preferred over oral supplements because it must be injected rectally under medical supervision.
When considering a butyric acid supplement, it is worth noting that not all oral supplements are formulated alike. The following table highlights the differences between the palatability and absorption of raw butyric acid and butyric acid supplements.
Comparison: Raw Butyric Acid versus Butyric Acid Supplement
Raw Butyric Acid
Butyric Acid Supplements
For more isobutyric acid manufacturerinformation, please contact us. We will provide professional answers.
Palatability
Highly pungent odor and acrid taste make it difficult to ingest.
Advanced supplement formulations make butyrate palatable.
Absorption
Quickly absorbed in the upper intestinal tract and rapidly eliminated from the body.
Encapsulated butyrate supplements enable targeted delivery of butyric acid molecules for enhanced absorption.*
Potential Benefits of Butyric Acid Supplements
The gut microbiome plays a critical role in the functioning of various organs. Researchers have found that butyric acid supplements can help enhance glutathione levels, which, in turn, can help limit oxidative damage to the gastrointestinal system and other organs5.*
In addition to influencing intestinal health and oxidative stress, the gut microbiome has been linked to modulating cognition through the &#;gut-brain axis&#;, potentially regulating behavior, learning and memory6.
The following table highlights how butyric acid supplementation can help promote gastrointestinal and neurological health.
Benefits of Butyric Acid Supplements
Gastrointestinal System
The presence of butyric acid in the gut inhibits the growth of pathogenic (bad) bacteria, which negatively affect gut health and function7.* Butyric acid supplementation promotes gastrointestinal health by:
- Addressing Oxidative Stress: Research has shown that butyrate can modulate the effects of oxidative stress in the colon8.*
- Acting as an Intestinal Barrier: Butyrate stimulates the production of mucin, the glycoproteins (mucus) produced by colon cells that act as a protective internal coating9.*
- Metabolic Regulation: Butyrate stimulates the colon to absorb sodium chloride (NaCl), a protective mechanism against dehydration9.*
- Immune Function: Butyric acid beneficially influences immune responses in intestinal mucosa by modulating the migration of immune cells, their adhesion, and cellular functions10.*
- Colonic motility: Butyric acid enhances colonic motility,the peristaltic motion of the intestine that allows for quick and easy passage of stool11.*
Neurological System
Butyrate has been shown to have beneficial effects on neurological health due to its neuroprotective effects and modulation of the gut-brain axis, supporting healthy cognitive function12.*
Future Explorations of Butyric Acid Benefits
The properties of butyric acid and its role in gastrointestinal and neurological health are well-established. In recent years, newer research is focusing on the previously unknown properties and health benefits of butyric acid. The following are some of the future explorations of butyric acid benefits:
- Butyric acid for weight management: The association between intestinal microflora and metabolic health has been recently established13. Butyrate exerts beneficial effects on cellular energy metabolism and intestinal homeostasis.* Low butyrate levels have been associated with several metabolic conditions, including blood glucose levels, insulin resistance, and weight gain14. Butyric acid supplementation has been found to promote healthy weight management15.*
- Butyric acid for heart health: Research studies show that butyric acid is absorbed into the portal vein, which can beneficially influence lipid metabolism, glucose homeostasis, and other critical metabolic processes.* Imbalance in the gut microbiota has been recognized as one of the factors involved in developing adverse cardiovascular conditions16. Butyric acid supplementation may exert cardioprotective effects by stabilizing microbial composition in the gut17.*
- Butyric acid for kidney health: Butyric acid exerts immunomodulatory effects and influences the activity of regulatory T cells (Tregs) and T-helper cells to help maintain normal inflammatory responses.* Research on its role as a potential immunoregulatory agent to address conditions arising from renal injury is ongoing18.
Frequently Asked Questions About Butyric Acid Supplements
The following are frequently asked questions about butyric acid supplements:
What is the recommended amount of butyric acid intake in supplement form?
The recommended amount of butyric acid in currently available nutritional supplements is 150-300 mg/ day19.
Are butyric acid supplements safe?
The safety profile of butyric acid is well-established. No toxicity or adverse side effects have been reported, and butyric acid supplements are well-tolerated, even when ingested in high amounts.
Can I take a butyric acid supplement with a prescription medicine?
It is always advised to consult with your health-care provider before including a butyric acid supplement in your diet or taking it with a prescription medicine and/or other nutritional supplements as interactions may exist.
How do I determine the best butyric acid supplement to support my health?
The key features of the best butyric acid supplement are:
- Enhanced absorption: Targeted delivery of butyric acid molecules at the desired point in the intestinal tract, which enables optimal absorption.
- Enhanced bioavailability: Optimal absorption translates to enhanced bioavailability of butyric acid molecules.
- Enhanced palatability: Supplement formulations that successfully mask the unpalatable taste and odor of butyric acid result in better regimen compliance.
ProButyrate® is an innovative butyric acid formulation developed by Tesseract Medical Research that enhances butyric acid&#;s absorption, bioavailability, and palatability. Tesseract&#;s proprietary CyLoc® &#; DexKey® nutrient delivery nanotechnology protects the integrity of the butyric acid molecules during transit through the stomach and enables their targeted delivery in the intestinal tract. The encapsulated butyrate molecules have enhanced palatability, making it easier to ingest orally. With improved bioavailability, ProButyrate® can help you realize the health benefits of butyric acid.*
The power of Tesseract supplements lies in enhancing palatability, maximizing absorption and bioavailability, and micro-dosing a nutrients in a single, highly effective capsule. Shop products on our website and learn more about how they can help support your gastrointestinal health.*
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Citations:
1Steliou K, et al. BioResearch Open Access vol. 1,4 (): 192-198. doi:10./biores..
2Donohoe DR, Garge N, Zhang X, et al. Cell Metab. ;13(5):517-526. doi:10./j.cmet..02.018
3Peng K, et al. Frontiers in Endocrinology vol. 14 . 24 Feb. , doi:10./fendo..
4Amiri P, et al. Frontiers in Pharmacology vol. 12 . 2 Feb. , doi:10./fphar..
5Chen Z, et al. Frontiers in Cell and Developmental Biology vol. 9 . 2 Nov. , doi:10./fcell..
6Carabotti, Marilia et al. Annals of gastroenterology vol. 28,2 (): 203-209.
7Zhu, Li-Bin et al. World journal of clinical pediatrics vol. 10,5 84-92. 9 Sep. , doi:10./wjcp.v10.i5.84
8Canani, Roberto Berni et al. World journal of gastroenterology vol. 17,12 (): -28. doi:10./wjg.v17.i12.
9Zeissig S, Fromm A, Mankertz J, et al. Gastroenterology. ;132(1):236-248. doi:10./j.gastro..10.033
10Böcker U, Nebe T, Herweck F, et al. Clin Exp Immunol. ;131(1):53-60. doi:10./j.-...x
11Sui SJ, Tian ZB, Wang QC, et al. Eur Rev Med Pharmacol Sci. ;22(14):-. doi:10./eurrev__
12Alpino GCÁ, Pereira-Sol GA, Dias MME, Aguiar AS, Peluzio MDCG. Beneficial effects of butyrate on brain functions: A view of epigenetic. Crit Rev Food Sci Nutr. ;64(12):-. doi:10./..
13Portincasa P, Bonfrate L, Vacca M, et al. Int J Mol Sci. ;23(3):. Published Jan 20. doi:10./ijms
14Brahe LK, Astrup A, Larsen LH. Obes Rev. ;14(12):950-959. doi:10./obr.
15Peng K, et al. Frontiers in Endocrinology vol. 14 . 24 Feb. , doi:10./fendo..
16Amiri P, et al. Frontiers in Pharmacology vol. 12 . 2 Feb. , doi:10./fphar..
17Aguilar EC, Leonel AJ, Teixeira LG, et al. Nutr Metab Cardiovasc Dis. ;24(6):606-613. doi:10./j.numecd..01.002
18Chen Z, et al. Frontiers in Cell and Developmental Biology vol. 9 . 2 Nov. , doi:10./fcell..
19Peng K, et al. Butyrate and obesity: Current research status and future prospect. Frontiers in Endocrinology vol. 14 . 24 Feb. , doi:10./fendo..
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